NOW Niacin  

A factor in the maintenance of good health. Helps normal growth and development. Helps the body to metabolize proteins, fats and carbohydrates. Flush-free niacin is popular, because it reduces the unpleasant flushing (reddening and warming of the skin) that is experienced by the majority of consumers after niacin supplementation.

Vitamin B3 is composed of niacin (nicotinic acid) and its amide, niacinamide, and can be found in many foods, including yeast, meat, fish, milk, eggs, green vegetables, and cereal grains. Inositol hexanicotinate consists of six  molecules of niacin (nicotinic acid) chemically linked to an inositol molecule. It is hydrolyzed in the body to free niacin and inositol, although this occurs slowly, with peak serum levels not occurring until approximately 10 hours after ingestion. It is theoretically possible that this slow conversion might reduce peak plasma levels and  thereby reduce the incidence of side effects that have been associated with niacin such as flushing. Inositol hexanicotinate has been shown to share some beneficial effects with niacin without causing the adverse effects, "flushing", associated with niacin administration. The majority (>80%) of subjects taking niacin experience cutaneous flushing and warm sensations, especially of the face, neck, and ears, upon initial ingestion and with dose escalation. This flushing and cutaneous warmth is usually mild in severity but has been reported intolerable enough to cause withdrawal of up to 50% of participants from clinical trials. The mechanism of action of inositol nicotinate is believed to be the same as that of niacin. NOW Flush-Free Niacin is from a vegetarian source.

Directions:

Inositol Hexanicotinate…………………………….…….. 320 mg

Providing:

Niacin…….….…………………………………..250 mg

Inositol………………………………………….67.5 mg

Non-Medicinal Ingredients: